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Overview of neoplasm

Definition A mass of tissue formed as a result of abnormal, excessive, uncoordinated, autonomous, and purposeless proliferation of cells even after removal of stimulus.  Neoplasm is a term while neoplasia is a process.  Tumour have two components, one is parenchyma (neoplastic cell) and second is stroma (supporting cells and vessels). Limitations of definition -   In most of the cases growth persists after removal of stimuli. In lot of cases we may not be able to recognize initiating stimuli. Difference between Neoplasia and Hyperplasia Features Neoplasia Hyperplasia Proliferation Uncontrolled Under controlled Coordination with surrounding tissue Uncoordinated Coordinated Proliferation after removal of stimulus Persists Stop Differentiation Varies Well-differentiated CLASSIFICATION Classification of tumour...

Complete Anatomy of Liver

Liver Liver is the largest internal organ of the body. Liver is the largest exocrine gland of the body. Liver is the main heat producing organ of the body. 1500 ml/min blood pass-out from the liver. 400 ml blood always present in the liver. Chief cells of the liver are called hepatocyte which forms 80% mass of the liver. In this article we are discussing about on these topics... Synonym Location Measurement Presenting parts Relation Ligaments Porta hepatis Hepatic segments Histology Functions Blood supply Lymphatic drainage Nerve supply Applied anatomy Front view of the liver Synonym Haper, hepta, biochemical lab, kitchen of the body. Location Right and left hypochondriac region and epigastric region . Posterior and inferior view of the liver Measurements Weight - 1200 - 1500gms ( male - 1400-1600, female - 1200 - 1400gms) Length - 26cm in male and 25cm in female average Thickness - 22cm in adult male and 21cm in ...

Sweet syndrome

  Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) What is Sweet Syndrome? Sweet Syndrome is a skin condition that causes painful, red or purple bumps and patches. It usually appears on the face, neck, and arms, and is often accompanied by fever and high levels of neutrophils in the blood.   Types of Sweet Syndrome: 1. Classic Sweet Syndrome: The most common form, often affecting young women, usually following mild illnesses or linked to pregnancy, inflammatory diseases, or infections. 2. Malignancy-Associated Sweet Syndrome: This type is connected to cancer, especially blood cancers like leukemia, and may even be the first sign of an underlying cancer. 3. Drug-Induced Sweet Syndrome: Caused by medications like granulocyte colony-stimulating factor (G-CSF), antibiotics, or cancer treatments.   Causes: Classic: Often no clear cause, but can be triggered by infections, pregnancy, or inflammation. Malignancy-Associated: Linked to cancers, especially...

Dengue Fever

 DENGUE FEVER   Contents: Introduction   Clinical presentation Diagnosis Treatment Diet  Introduction: Dengue fever is a viral infection caused by dengue virus. Dengue virus is an RNA virus of genus flavi virus. — There are four serotypes dengue virus that is DENV-1, DENV-2, DENV-3, DENV-4 — Dengue virus transmitted by Aedes aegypti mosquito   Aedes aegypti mosquito   Aedes aegypti mosquito known to transmit Dengue virus, Yellow fever virus,  Chikungunya  virus, and Zika virus and it also suggest as a potential vector of Venezuelan Equine Encephalitis   virus and studies shown it is capable to transmit West Nile virus as well. Clinical Presentation: Divides into 4 categories :   Dengue without warning sign   Dengue with warning sign   Severe dengue / dengue hemorrhagic fever Dengue shock syndrome   Remember Note: Not all patient goes in all these phases. —   Majority of patient develops dengue withou...