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Parkinson's disease or Parkinsonism

Parkinson's disease or Parkinsonism

Parkinson's disease was discovered by James Parkinson. Name of this disease are given on the name of it's discoverer. This disease are also called Paralysis Agitates.
Parkinsons disease occurs due to damage of basal ganglia. It is mostly due to the destruction of substantial nigra and nigro-strial pathway, which has dopaminergic fibers.

Causes

  1. Injury to basal ganglia
  2. Cerebral arteriosclerosis
  3. Viral infection of brain like encephalitis

Symptoms

  1. Rigidity of muscles
  2. Tremors
  3. Akinesia or hyperkinesia
  4. Abnormal gait
  5. Emotional changes

Treatment

Parkonism disease is due to the damage of dopaminergic fibers, so it's treated by dopamine.
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