Definition A mass of tissue formed as a result of abnormal, excessive, uncoordinated, autonomous, and purposeless proliferation of cells even after removal of stimulus. Neoplasm is a term while neoplasia is a process. Tumour have two components, one is parenchyma (neoplastic cell) and second is stroma (supporting cells and vessels). Limitations of definition - In most of the cases growth persists after removal of stimuli. In lot of cases we may not be able to recognize initiating stimuli. Difference between Neoplasia and Hyperplasia Features Neoplasia Hyperplasia Proliferation Uncontrolled Under controlled Coordination with surrounding tissue Uncoordinated Coordinated Proliferation after removal of stimulus Persists Stop Differentiation Varies Well-differentiated CLASSIFICATION Classification of tumour...
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